Flavour peptides: the potential role of Lactococcal peptidases in their production.

نویسنده

  • F Mulholland
چکیده

11. Mellor, J., Dobson, M. J., Roberts, N. A., Tuite, M. F., Emtage, J. S., White, S., Lowe, P. A., Patel, T., Kingsmann, A. J. & Kingsman, S. M. (1983) Gene 24, 1-14 12. Goff, C. G., Moir, D. T., Kohno, T., Fravius, T. C., Smith, K. A,, Yamasaki, E. & Taunton-Rigby, A. (1984) Gene 27,35-46 13. Moir, D. T., Mao, J., Duncan, M. J., Smith, R. A. & Kohno, T. (1985) in Developments in Industrial Microbiology(Underkofler, I,., ed.), vol. 6, pp. 75-85, Society for Industrial Microbiology, Arlington, VA, U.S.A. 14. van den Berg, J. A., van der Laken, K. J., van Ooyen, A. J. J., Renniers, T. C. H. M., Kietveld, K.. Schaap, A., Brake, A. J., Bishop, R. J., Schultz, K., Moyer, D., Richman, M. & Schuster, J. R. (1990) Bio/Technology 8,135-139 15. Cullen, D.. Gray, G. I,., Wilson, L. J., Hayenga, K. J., Lamsa, M. H., Key, M. W., Norton, S. & Berka, R. M. (1987) Bio/Technology 5, 369-376 16. Harkki, A,, Uusitalo, J., Bailey, M., Penttila, M. & Knowles, J. K. C. (1989) Bio/Technology 7,596-603 17. Berka, R. M., Ward, M., Wilson, I,. J., Hayenga, K. J., Kodama, K. H., Carlomagno, I,. P. & Thompson, S. A. (1990) Gene 86, 153-162 18. Ward, M., Wilson, L. J., Kodama, K. H., Key, M. W. & Rerka, R. M. (1990) Bio/Technology 8,435-440 19. Bech, A. M. & Foltmann, B. (1981) Neth. Milk Dairy J. 35,275-280 20. Hiramatsu, R., Aikawa, J., Horinouchi, S. & Beppu, T. ( 1989) J. Biol. Chem. 264, 1686216866 21. Gray, G. L., Hayenga, K., Cullen, D., Wilson, I,. J. & Norton, S. (1986) Gene 48,41-53 22. Christensen, T., Woldike, H., Boel, E., Mortensen, S. B., Hjortshoj, K., Thim, I,. & Hansen, M. T. (1988) Bio/Technology 6,14 191422 23. Boel, E., Christensen, T. & Woldike, H. (1987) Eur. Pat. Application, Publication Number 0 238 123 24. Ward, M. & Kodama, K. H. (1991) in Structure and Function of the Aspartic Proteinases: Genetics, Structure, Mechanisms (Lhnn, R., ed.), Plenum Press, New York, in the press 25. Yamashita, T., Tonouchi, N., Uozumi, T. & Beppu, T. (1987) Mol. Gen. Genet. 210,462-4567 26. Gilliland, G. L., Winborne, E. L. & Nachman, J. & Wlodawer, A. (1990) Proteins 8,82-101

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Plant-based expression systems for protein and antimicrobial peptide production

Molecular farming technology offers a unique advantage that almost any protein can be produced economically and safely under very controlled conditions. Besides traditional production systems, such as bacteria, yeasts, insects and mammal cell lines, plants can now be used to produce eukaryotic recombinant proteins, especially therapeutic ones. Their advantages as hosts for protein production in...

متن کامل

Multiple-peptidase mutants of Lactococcus lactis are severely impaired in their ability to grow in milk.

To examine the contribution of peptidases to the growth of lactococcus lactis in milk, 16 single- and multiple-deletion mutants were constructed. In successive rounds of chromosomal gene replacement mutagenesis, up to all five of the following peptidase genes were inactivated (fivefold mutant): pepX, pepO, pepT, pepC, and pepN. Multiple mutations led to slower growth rates in milk, the general ...

متن کامل

P135: The Role of Amyloid Beta-Peptides and Tau Protein in Alzheimer\'s Disease

Alzheimer's desease is the most common age-related neurodegenerative disorder, and cognitive problems such as defects in learning and memory are of its symptoms.  Among the factors involved in the pathogenesis of the disease are biochemical disorders in protein production, oxidative stress, decreased acetylcholine secretion and inflammation of the brain tissue. Extra-neuronal accumulation ...

متن کامل

Stimulation of interleukin-10 production by acidic beta-lactoglobulin-derived peptides hydrolyzed with Lactobacillus paracasei NCC2461 peptidases.

We have previously demonstrated that Lactobacillus paracasei NCC2461 may help to prevent cow's milk allergy in mice by inducing oral tolerance to beta-lactoglobulin (BLG). To investigate the mechanisms involved in this beneficial effect, we examined the possibility that L. paracasei induces tolerance by hydrolyzing BLG-derived peptides and liberating peptides that stimulate interleukin-10 (IL-1...

متن کامل

Biochemical and genetic characterization of PepF, an oligopeptidase from Lactococcus lactis.

Lactococcus lactis possesses a complex proteolytic system which is essential for its growth in milk. We characterized one of the peptidases of this system, oligopeptidase PepF, together with its structural gene. PepF hydrolyzed peptides containing between 7 and 17 amino acids with a rather wide specificity. It was purified to homogeneity. The N-terminal sequences of PepF and of peptides resulti...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Biochemical Society transactions

دوره 19 3  شماره 

صفحات  -

تاریخ انتشار 1991